Endocrine Abstracts

A 42 year old male patient was admitted to the gastroenterology unit in due to severe abdominal pain and vomiting. He denied any chronic illness and drug usage. His family history was nonsignificant for any endocrine disease. Based on biochemical studies (lipase 2280 U/l, calcium 15.0 mg/dl, phosphorus 1.7 mg/dl amylase 631 U/l, creatinine 1.16 mg/dl, ALP 735 U/l) severe hypercalcemia induced acute pancreatitis was the diagnosis. 25 OH vitamin D was 5 ng/ml and parathyroid hor...

Introduction: Primary hyperparathyroidism (PHPT) occurs a peak incidence between ages 50 and 60 and the classical bone disease of PHPT or pathological fractures due to PHPT is rarely seen today. Furthermore brown tumor detected with Tc-99m MIBI scintigraphy exists in literature infrequently.Case: A 23 years old woman presented with left arm pain admitted in Department of Orthopaedics for pathological fracture in left humerus. As a result of investigation...

Introduction: Isolated ACTH deficiency (IAD) is a rare disease which is characterized by secondary adrenal insufficiency with low cortisol production and normal secretion of pituitary hormones except ACTH. Isolated ACTH deficiency has rare association with Hashimoto’s disease which is characterized by autoimmune origin. This suggests the possibility of common autoimmune process affecting both the pituitary and the thyroid gland. We report a case of IAD with Hashimoto&#146...

Introduction: Thyroid disorders such as subacute thyroiditis occur rarely in pregnancy. We report a recurrent case of subacute thyroiditis improved with the onset of pregnancy.Case report: A 32-year-old Turkish women who request pregnancy and planned insemination was referred due to malaise and neck pain in the left side a week ago. She was presented with low-grade fever, fatigue, pharingitis symptoms, neck pain and extremely tenderness in the right side...

Introduction: The most common cause of thyotoxicosis is Graves’ disease. Thyroid storm mostly presents with fever, tachycardia, arrthyhmia, jaundice, congestive heart failure and consciousness. We report a rare case of severe hypoalbuminemia with thyroid storm. To our knowledge it is the first case of severe hypoalbunemia due to thyrotoxicosis in literature.Case: Forty one years old female had been followed up with the diagnosis of Graves’ dise...

Aim: The aim of this study was to examine serum fetuin-A, leptin and hs-CRP concentrations among pregnant women with gestational diabetes (GDM), and to evaluate the relationship between these parameters and insulin resistance.Materials and methods: In this study, we evaluated 47 pregnant patients with GDM. As the control group, 43 normal pregnant women having similar properties with these GDM patients, but not gestational diabetes were enrolled. Serum fe...

Objective: Altered hearing function in diabetic patients has been found in both pure tone audiometry and otoacoustic emissions (OAEs). We intended to evaluate the cochlear function with both DPOAE and TEOAE in patients with DM without polyneuropathy and hypertension.Patients and methods: Study group consisted of type 2 diabetic patients and healthy control group consisted of healthy age and sex matched volunteers. Detailed ear examination, pure tone audi...

Introduction: Diabetic nephropathy is the leading cause of chronic renal failure worldwide. Related to the increased glucose and its metabolites, activation of renin–angiotensin–aldosterone system, and increased oxidative stress are important in renal deterioration. The studies indicate that suppression of renin–angiotensin–aldosterone system slow down diabetic nephropathy; Nigella sativa decreases blood glucose and oxidative stress. Were viewed th...

Aim: Nonenzymatic advanced glycation and oxidation end-products, advanced glycation end-products (AGEs), impart a potent impact on vessels in diabetic state and in euglycaemic conditions with increased oxidative stress.The aim of this study is to measure AGEs and its relationship with carotid intimae media thickness (CIMT) in acromegaly patients.Method: A case–control study was performed in 225 acromegalic patients (F/M: 116/1...

Introduction: Insulin resistance, refers to decreased response of tissues to insulin, primarily associated with type 2 diabetes and glucose intolerance. Several results were obtained in previous studies about the relation between insulin resistance and thyroid dysfunction. In these studies hepatosteatosis was not an exclusion criteria despite insulin resistance has a key role in the development of it. In this study we aimed to investigate insulin resistance in patients with hy...